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News Physiol Sci 15: 213-218, 2000;
1548-9213/00 $5.00
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News in Physiological Sciences, Vol. 15, No. 5, 213-218, October 2000
© 2000 Int. Union Physiol. Sci./Am. Physiol. Soc.

Mast Cell-Nerve Interactions

Omri Bauer and Ehud Razin

O. Bauer and E. Razin are in the Department of Medical Biochemistry, The Hebrew University-Hadassah Medical School, P.O. Box 12272, Jerusalem 91120, Israel.
Mutual associations between nerves and mast cells have been observed in normal conditions and in pathological ones such as human irritable bowel syndrome, atopic dermatitis, interstitial cystitis, and more. Here we review the recent literature in this field, putting emphasis on the enteric, skin, and urinary systems, and the pathophysiological implications of this interaction in them.




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