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Physiology 19: 348-354, 2004; doi:10.1152/physiol.00021.2004
1548-9213/04 $5.00
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Physiology, Vol. 19, No. 6, 348-354, December 2004
© 2004 Int. Union Physiol. Sci./Am. Physiol. Soc.

REVIEW

Common Cues in Vascular and Axon Guidance

Guido Serini and Federico Bussolino

Division of Molecular Angiogenesis, Institute for Cancer Research and Treatment, and Department of Oncological Sciences, University of Torino School of Medicine, 10060 Candiolo (TO), Italy

guido.serini{at}ircc.it federico.bussolino{at}ircc.it

Blood vessels and nerves are structured in architecturally similar organ systems and show functional relationships. Indeed, vascular and neuronal cells are guided in their journey throughout the body by the same attractive and repulsive factors that respectively activate and inhibit the function of integrin-adhesive receptors.




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A. de Candia, A. Gamba, F. Cavalli, A. Coniglio, S. Di Talia, F. Bussolino, and G. Serini
A Simulation Environment for Directional Sensing as a Phase Separation Process
Sci. Signal., March 20, 2007; 2007(378): pl1 - pl1.
[Abstract] [Full Text] [PDF]


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