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Physiology 21: 281-288, 2006; doi:10.1152/physiol.00059.2005
1548-9213/06 $8.00
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Physiology, Vol. 21, No. 4, 281-288, August 2006
© 2006 Int. Union Physiol. Sci./Am. Physiol. Soc.

REVIEW

The Interaction Between Pathogens and the Host Coagulation System

Hongmin Sun

Life Sciences Institute, University of Michigan, Ann Arbor, Michigan hongmin{at}umich.edu

There is mounting evidence that the hemostatic system is critical in host responses to bacterial infection. Invasive bacteria have evolved virulence strategies to interact with host hemostatic factors such as plasminogen and fibrinogen for infection. Furthermore, genetic variations in host hemostatic factors also influence host response to bacterial infection.




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