Physiology Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Physiology 23: 142-150, 2008; doi:10.1152/physiol.00001.2008
1548-9213/08 $8.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Google Scholar
Right arrow Articles by Baylis, C.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Baylis, C.
Physiology, Vol. 23, No. 3, 142-150, June 2008
© 2008 Int. Union Physiol. Sci./Am. Physiol. Soc.

REVIEW

Sexual Dimorphism of the Aging Kidney: Role of Nitric Oxide Deficiency

Chris Baylis

University of Florida, Gainesville, Florida baylisc{at}ufl.edu

GFR falls with aging in humans and rats due to renal vasoconstriction and structural damage. The rate of deterioration is influenced by race/genetic background, environment, and sex, with females protected. Part of the female advantage relates to protective effects of estrogens. There is little information on impact of aging on the distribution/cardiovascular actions of the estrogen receptor subtypes. In rats, androgens may contribute to injury, but in men, high testosterone levels predict cardiovascular health. In women, the association is controversial. Nitric oxide deficiency contributes to the hypertension and renal dysfunction of aging, which may be delayed in the female.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2008 by the Int. Union Physiol. Sci./Am. Physiol. Soc.