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Physiology 23: 263-274, 2008; doi:10.1152/physiol.00016.2008
1548-9213/08 $8.00
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Physiology, Vol. 23, No. 5, 263-274, October 2008
© 2008 Int. Union Physiol. Sci./Am. Physiol. Soc.

REVIEW

Brain Protection by Erythropoietin: A Manifold Task

Tamer Rabie and Hugo H. Marti

Institute of Physiology and Pathophysiology, University of Heidelberg, Heidelberg, Germany hugo.marti{at}physiologie.uni-hd.de

Many hematopoietic growth factors are produced locally in the brain. Among these, erythropoietin (Epo), has a dominant role for neuroprotection, neurogenesis, and acting as a neurotrophic factor in the central nervous system. These functions make erythropoietin a good candidate for treating diseases associated with neuronal cell death.






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